The Mastrojanni Estate was established in 1975 through the combination of the Loreto and San Pio manor farms, near the village of Castelnuovo dell'Abate.

In 2011 began a complex program of architectural renovations for development of the Relais Mastrojanni. Completed in 2019, the Relais brings important new life to the Loreto and San Pio farms.
The ancient walls have been restored with elegant simplicity, creating bright rooms with clean, modern lines and soft colours.